SUPERIOR
CLINICALLY
MEANINGFUL
Ozempic® demonstrated superior weight loss vs Trulicity®2
*P<0.0001
THE WEIGHT LOSS
VS TRULICITY®†
†Results apply to 1-mg dose of Ozempic® vs Trulicity® 1.5 mg.
Change from baseline in weight at Week 40
Mean baseline: 95.2 kg
–2.3 kg
–4.6 kg*
–3.0 kg
–6.5 kg*
Trulicity®
0.75 mg
Ozempic®
0.5 mg
Trulicity®
1.5 mg
Ozempic®
1 mg
n=299
n=301
n=299
n=300
VS JANUVIA®
VS INVOKANA®
ADA/EASD REPORT
SUPERIOR
CLINICALLY
MEANINGFUL
Ozempic®—more than twice as many patients experienced clinically
meaningful weight loss vs Trulicity®2
P<0.0001
Of patients treated with Ozempic® 1 mg...
EXPERIENCED
Compared with 8% of patients
treated with Trulicity® 1.5 mg
EXPERIENCED
Compared with 30% of patients
treated with Trulicity® 1.5 mg
x 
Ozempic® demonstrated superior HbA1c reductions vs Januvia®
Change from baseline in HbA1c at Week 561
HbA1c REDUCTIONS
VS JANUVIA®1†
–0.5%
–1.3%*
–1.6%*
Januvia®
100 mg
Ozempic®
0.5 mg
Ozempic®
1 mg
Mean baseline: 8.3%
n=407
n=409
n=409
*P<0.0001
Ozempic® demonstrated superior weight loss vs Januvia® sustained over 1 year1
Change from baseline in weight at Week 561
VS JANUVIA®1†
– 1.9 kg
– 4.3 kg*
– 6.1 kg*
Januvia®
100 mg
Ozempic®
0.5 mg
Ozempic®
1 mg
Mean baseline: 89.5 kg
n=407
n=409
n=409
*P<0.0001
ABSOLUTE HbA1c
ABSOLUTE WEIGHT LOSS
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x 
Once-weekly Ozempic® delivered superior HbA1с reductions vs Invokana®
Change from baseline in HbA1c at Week 5228
REDUCTIONS
VS INVOKANA®1
– 1.0%*
– 1.5%*
Invokana®
300 mg
Ozempic®
1 mg
Mean baseline: 8.3%
n=394
n=394
*P<0.0001
Ozempic® delivered superior weight loss vs Invokana®
Change from baseline in weight at Week 5228
WEIGHT
LOSS
WITH OZEMPIC®1 MG
VS INVOKANA®1
– 4.2 kg*
– 5.3 kg*
Invokana®
300 mg
Ozempic®
1 mg
Mean baseline: 90.2 kg
n=394
n=394
*P=0.0029
ABSOLUTE HbA1c
ABSOLUTE WEIGHT LOSS
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x 
2019 update to the 2018 ADA/EASD consensus report6
For adults with type 2 diabetes and a need to prioritise weight loss
THE 2019 UPDATE TO THE
2018 ADA/EASD CONSENSUS REPORT
RECOMMENDS A
GLP-1 RA
WITH GOOD EFFICACY
FOR WEIGHT LOSS6*
*Semaglutide
liraglutide
dulaglutide
exenatide
lixisenatide